Health literacy and guideline-adherent lifestyle in people with chronic kidney disease: exploring factors associated with usage intention of a structured m-health program and pilot data on actual behavior change

Health literacy and guideline-adherent lifestyle in people with chronic kidney disease: exploring factors associated with usage intention of a structured m-health program and pilot data on actual behavior change

Photo of PD Dr. Laura Schmidt
PD Dr. Laura Schmidt

Gesundheitspsychologin (Dipl.-Psych)

Photo of Dr. med Anh-Thu Hentschel
Dr. med Anh-Thu Hentschel

Nephrologin,
Nephrologicum Lausitz

Photo of Prof. Dr. med Jürgen Wagner
Prof. Dr. med Jürgen Wagner

Chefarzt Innere Medizin, Heidelberg

Photo of Dr. med Daniela Rose
Dr. med Daniela Rose

Diabetologin und Nephrologin, NEDD*Grünstadt

Background

Although medical guidelines for chronic kidney disease (CKD) clearly recommend measures such as blood pressure control, dietary changes, regular physical activity, and consistent medication adherence, individuals frequently encounter challenges in implementing these behavioral modifications. In medical practices, there is a lack of time and resources to comprehensively support CKD patients and low-threshold (digital) interventions aimed at enhancing patient activation are needed. This paper analyzes the acceptance and usage intention (Study 1) and the contribution to health literacy and behavioral change (Study 2) of a m-health program for CKD (“Oska”). The Oska program combines personal counseling via video calls with app-based support and is theoretically grounded in the Health Action Process Approach (HAPA), with a strong emphasis on fostering self-efficacy and promoting implementation in daily routines.




Method

Study 1: An online survey was conducted with N = 401 individuals with CKD and/or hypertension, obesity, type 2 diabetes, or coronary heart disease (age: 50–89 years, M = 64.1, 49% female). Participants were recruited via the provider Appinio and presented with a vignette illustrating the Oska program and answered questionnaires on usage intention, desired support, compatible health benefits, health literacy, and perceived usefulness. Study 2: N = 109 participants with CKD, who already took part in the Oska program for an average of 4.7 months (age: 29–84 years, M = 62.3, 64% female, BMI: M = 29.6), completed established questionnaires on working alliance, kidney-specific health literacy, and behavior change. The analysis was conducted using structural equation models and linear regression analyses.




Results

Acceptance and usage intention in study 1 were high and predominantly explained by compatible health benefits, health literacy, and perceived usefulness, but largely independent of sociodemographic factors and health-related variables. In study 2, higher health literacy was primarily fostered by longer program participation and, most notably, by a positive trust relationship (working alliance) (adj = .48) Successful behavior change (across all guideline areas) was primarily attributed to a positively evaluated working alliance and Oska’s contribution to health literacy, rather than sociodemographic factors or the number and type of diagnoses (adj = .14).


Discussion

Digitally delivered coaching combined with app-based support is not only acceptable but may be particularly effective for CKD patients with low health literacy and multiple comorbidities. Relevant determinants include a trusting coaching relationship and a focus on health literacy as well as self-efficacy in implementing measures in everyday life.




Full study published in Frontiers in nephrology


ORIGINAL RESEARCH article

Front. Nephrol., 03 September 2025

Sec. Clinical Research in Nephrology

Volume 5 - 2025 | https://doi.org/10.3389/fneph.2025.1629438

link zu frontiers

Photo of PD Dr. Laura Schmidt
PD Dr. Laura Schmidt

Gesundheitspsychologin (Dipl.-Psych)

PD Dr. Laura Schmidt hat bei Oska die verhaltenswissenschaftliche Leitung inne. Außerdem arbeitet sie in der Abteilung Gesundheitspsychologie am Psychologischen Institut der Universität Heidelberg. Ihre Forschungsschwerpunkte sind (1) Technikakzeptanz und Umgang mit Technik im höheren Lebensalter, (2) Bewegungsförderung bei älteren Erwachsenen und Zusammenhänge mit den SIchtweisen auf das Älterwerden sowie (3) Selbstregulation, Stresserleben und Schlafverhalten.

Photo of Dr. med Anh-Thu Hentschel
Dr. med Anh-Thu Hentschel

Nephrologin,
Nephrologicum Lausitz

Dr. Anh-Thu Hentschel ist Fachärztin im Nephrologicum Lausitz, zuvor war sie im Carl-Thiem-Klinikum Cottbus tätig. Ihre Schwerpunkte sind Peritonealdialyse und Ernährung in der ambulanten Versorgung. Als medizinische Beraterin unterstützt sie Oska dabei, Menschen mit chronischen Erkrankungen individuell zu begleiten.

Photo of Dr. med Daniela Rose
Dr. med Daniela Rose

Diabetologin und Nephrologin, NEDD*Grünstadt

Daniela Rose ist Fachärztin für Innere Medizin, Nephrologie, Endokrinologie und Diabetologie und seit 8 Jahren bei NEDD*Grünstadt tätig. Sie hat mehr als 20 Jahre klinische Erfahrung, unter anderem früher als Oberärztin bei der Universitätsmedizin Mannheim.